Università degli Studi di Pavia - Faculty of Science

Home

HomeCoursesList of courses › Structural Biology and Pharmacology

Structural Biology and Pharmacology

Teachers:
Andrea Mattevi, Sunil Sharma
Year:
2017/2018
ECTS:
6
SSD:
BIO/11

Course content

This course investigates the fundamental concepts and methods for the study of the structures of biological macromolecules with a focus on the implications for drug development and design.
Methods for the study of the three-dimensional structure of biological macromolecules. Introduction to biocrystallography. Diffraction theory. The phase problem and methods for its solution. Experimental methods in biocrystallography. NMR spectroscopy. Multidimensional NMR. Other methods for structural biology (electron microscopy, mass spectrometry). Structure-based drug design. Examples of the application of the structural biology methods for drug development.


Credits: apnetwork.it