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Ermanno Gherardi

Academic position:
Full Professor
E-mail:
egherard (at) unipv.it
Phone number:
+39 0382 986845
Fax:
+39 0382 986893
Website:
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Department:
Department of Molecular Medicine

Courses

2017/2018
Immunology
2016/2017
Immunology

Exams

No exams

Curriculum vitae

General

Date of birth: 26 October 1952
Nationality: Italian
Degrees: MB, MA & PhD (Cantab)

 

Work Address and contacts

Unit of Immunology and General Pathology, Department of Molecular Medicine, University of Pavia, 9 via A Ferrata, 27100 Pavia, Italy.

Departmental Website: http://medmol.unipv.eu/site/home.html

 

Research Projects

1. Understanding the structural basis of the maturation of the antibody response in a model system (the mouse response to the happen 2-phenyl-oxazolone.

2. Developing antibodies to therapeutic targets, such as growth factors and receptors, involved in tissue regeneration and cancer.

3. Understanding the molecular basis of the behaviour of complex cellular systems and notably regulation of cell number and migration.
 

Selected Publications

Michael Stoker. Weiss R and Gherardi E. Cell 155:493-4 (2013)

Targeting MET in cancer: rationale and progress. Gherardi E et al. Nat Rev Cancer 12:89-103 (2012)

Structure of the human receptor tyrosine kinase Met in complex with the Listeria monocytogenes invasion protein InlB. Niemann H et al. Cell 130: 235-46, 2007

Structural basis of HGF/SF and MET signalling. Gherardi E et al. PNAS 103:4046-4051 (2006)

Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for HGF/SF. Gherardi E et al. PNAS 100: 12039-44 (2003)

Scatter factor/hepatocyte growth factor is essential for liver development.
Schmidt, C et al. Nature 373: 699-702 (1995)

Isolation of high affinity human antibodies directly from large synthetic repertoires. Griffiths AD et al EMBO J 13: 3245-60 (1994)

Original and artificial antibodies. Gherardi E and Milstein C. Nature 357, 201-2 (1992)

Mutation and selection during the secondary response to 2-phenyloxazolone. Rada C et al. PNAS 88, 5508-12 (1991)

Scatter factor is a fibroblast-derived modulator of epithelial cell motility. Stoker M et al. Nature 327, 239-242 (1987)
 

Credits: apnetwork.it