Università degli Studi di Pavia - Faculty of Science


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Cinzia Calvio

Academic position:
Assistant Professor
cinzia.calvio (at) unipv.it
Phone number:
+39 0382 985545
+39 0382 528496
Department of Biology and Biotechnology "Lazzaro Spallanzani"


Microbial Genetics
Microbial Genetics
Microbial Genetics


No exams

Curriculum vitae

"Assistant Professor" in Genetics, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy
Cinzia Calvio obtained her first degree cum laude in Biology from the University of Pavia in 1990. In 1993 she obtained the degree in Applied Genetics from the Specialization School in “Applied Genetics” at the University of Pavia. The Specialization thesis work was carried out at the IGM-CNR, in Pavia. From Sept. ’92 to Dec. ’95, she held a Postdoc position at the European Molecular Biology Laboratory (EMBL), Heidelberg (D). A second Postdoc (Feb. ‘96 - May ’97) was carried out at the European Institute of Oncology - IEO, Milan. In June 1997 she worked for commercial company as Product specialist for automated DNA sequencers and instrumentation for analyses of macromolecular interactions. In 1999 she obtained a Research assistant position at the Dept. of Genetics and Microbiology of the University of Pavia, being in charge of the supervision of the departmental sequencing facility. In 2003 she joined, as Assistant Professor in Genetics, the lab of Microbial Genetics at the Dept. of Biology and Biotechnology (formerly Dept. of Genetics and Microbiology) of the University of Pavia. After a long collaboration with Prof. A. Galizzi, from 2009 she is the PI of the Microbial Genetics Laboratory. Her main research interest has been the regulation of stationary phase phenotypes in the model organism Bacillus subtilis. After several years of contributing to the teaching of Genetics and Functional genomics for bachelor degree courses at the Biology and the Biotechnology programs, since 2009 she holds the chair of “Microbial Genetics” for the Master programme in Molecular Biology and Genetics. From 2016 she will also be involved in teaching Microbial biodiversity and genetics in soil at the Master program in Natural Sciences.
Selected publications
  1. Casanova, M., Pasotti, L., Zucca, S., Politi, N., Massaiu, I., Calvio, C., Cusella De Angelis, M.G., Magni. A BioBrick™-Compatible Vector for Allelic Replacement Using the XylE Gene as Selection Marker. P. Biological Procedures Online, 2016; 18:6. DOI 10.1186/s12575-016-0036-z.
  2. Mamberti S., Prati P., Cremaschi P., Seppi C., Morelli C.F., Galizzi A., Fabbi M., Calvio C. γ-PGA Hydrolases of Phage Origin in Bacillus subtilis and Other Microbial Genomes. PLoS ONE, 2015; 10(7):e0130810. DOI:10.1371/journal.pone.0130810.
  3. Mordini S., Osera C., Marini S., Scavone F., Bellazzi R., Galizzi A., Calvio C. The Role of SwrA, DegU and PD3 in fla/che Expression in B. subtilis. PLoS ONE, 2013; 8(12):e85065. DOI:10.1371/journal.pone.0085065 .
  4. Morelli C.F., Calvio C., Biagiotti M., Speranza G. pH-Dependent hydrolase, glutaminase, transpeptidase and autotranspeptidase activities of Bacillus subtilis γ-glutamyltransferase. FEBS J. 2014; 281(1):232-45; DOI:10.1111/febs.12591.
  5. Scoffone V., Dondi D., Biino G., Pasini D., Galizzi A., Calvio C. Knockout of pgdS and ggt genes improves γ-PGA yield in B. subtilis. Biotechnology and Bioengineering, 2013; 110(7). DOI:10.1002/bit.24846.
  6. Osera C., Amati G., Calvio C., Galizzi A. SwrAA activates poly- -glutamate synthesis in addition to swarming in Bacillus subtilis. Microbiology, 2009; 155(Pt 7):2282-7. DOI:10.1099/mic.0.026435-0.
  7. Calvio C., Osera C., Amati G., Galizzi A. Autoregulation of swrAA and Motility in Bacillus subtilis. Journal of bacteriology, 2008; 190(16):5720-8. DOI:10.1128/JB.00455-08.
  8. Calvio C., Celandroni F., Ghelardi E., Amati G., Salvetti S., Ceciliani F., Galizzi A., Senesi S. Swarming Differentiation and Swimming Motility in Bacillus subtilis Are Controlled by swrA, a Newly Identified Dicistronic Operon. Journal of Bacteriology, 2005; 187(15):5356-66. DOI:10.1128/JB.187.15.5356-5366.2005.
  9. Davies R.C., Calvio C., Bratt E., Larsson S.H., Lamond A.I., Hastie N.D. WT1 interacts with the splicing factor U2AF in an isoform-dependent manner and can be incorporated into spliceosomes. Genes & Development, 1998; 12(20):3217-25. DOI:10.1101/gad.12.20.3217.
  10. Neubauer G., King A., Rappsilber J., Calvio C., Watson M., Ajuh P., Sleeman J., Lamond A.I., Mann M. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. Nature Genetics, 1998; 20(1):46-50. DOI:10.1038/1700.



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